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KMID : 0984720050370010047
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Infection and Chemotherapy
2005 Volume.37 No. 1 p.47 ~ p.49
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An Outbreak of Acute Febrile Reaction Developed after the Administration of Teicoplanin
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Kim Baek-Nam
Na Hyun-Hee
Ahn Jung-Mi
Ahn Jung-Mi
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Abstract
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An outbreak of acute febrile reaction which developed after the administration of teicoplanin was identified in seven patients. Fever, with hypotension in some, developed during or soon after infusion and persisted for several hours. Laboratory abnormalities including leukocytosis and elevation of liver enzymes and creatine phosphokinase in serum were observed for two or three days. Contamination of the drug with endotoxins was identified.
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KEYWORD
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Teicoplanin, Fever, Drug contamination, Endotoxins
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